For a decade, Ecco has published the most outstanding science writing in America, collected in highly acclaimed annual volumes edited by some of the most impressive and most important names in science and science writing today: James Gleick, Timothy Ferris, Matt Ridley, Oliver Sacks, Dava Sobel, Alan Lightman, Atul Gawande, Gina Kolata, Sylvia Nasar, and Natalie Angier.

Now series editor Jesse Cohen invites the previous guest editors to select their favorite essays for this one-of-a-kind anthology. The result is an outstanding compendium—the best science writing of the new millennium, featuring an introduction by the series' 2010 editor and New York Times bestselling author of How Doctors Think, Jerome Groopman.